Table 3.

Median Survival and Univariate Analysis

Characteristics	n	Median Survival (95% CI)	P value Univariate
Female	11	26.7 mo (10–39)	0.07
Male	12	22.7 mo (12.7-NA)
No comorbidities	18	39.1 mo (15.1–58.5)	0.56
Any comorbidity	5	17.9 mo (2.1-NA)
Family history	4	40.4 mo (15.1-NA)	0.20
No family history	19	22.7 mo (13.5–39.1)
Liver only disease	4	20.8 mo (2.1-NA)	0.83
Metastatic spread	19	26.7 mo (15.1–40.4)
Node metastasis	9	29.6 mo (12.7-NA)	0.35
No node metastasis	14	22.7 mo (10–40.4)
Lung metastasis	9	39.1 mo (10-NA)	0.09
No lung metastasis	14	19.8 mo (12.7–58.5)
Peritoneal metastasis	5	19.8 mo (4.0-NA)	0.07
No peritoneal metastasis	18	39.1 mo (15.1–40.4)
Multinodular	11	22.7 mo (10.0–64.8)	0.47
Uninodular	12	29.6 mo (12.7–39.1)
Macrovascular invasion	7	26.7 mo (12.7–39.1)	0.84
No macrovascular invasion	16	40.4 mo (15.1-NA)
NLR high*	7	22.7 mo (2.1-NA)	0.02 (HR: 1.8; 95% CI 1.1–4.3).
NLR low	6	39.1 mo (29.6-NA)

Notes: Multivariate analysis was not performed because NLR was the only significant variable. *10 patients did not have baseline blood cell count available.

Abbreviations: CI, confidence interval; NLR, neutrophil-to-lymphocyte ratio; NA, not achieved; HR, Hazard ratio.