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. 2023 May 12;103(4):2623–2677. doi: 10.1152/physrev.00032.2022

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Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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FIGURE 9. — Stages of meiosis. As oocytes are formed during fetal life they enter meiosis, reach the dictyate stage of prophase 1, and are then held in meiotic arrest. Meiosis resumes in response to the luteinizing hormone (LH) surge at the time of ovulation and progresses through the first meiotic division with emission of the first polar body and the formation of the metaphase II spindle and arrested for a second time. Final resumption and completion of meiosis is triggered by fertilization. Image created with BioRender.com, with permission.