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. 2023 May 12;103(4):2623–2677. doi: 10.1152/physrev.00032.2022

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Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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FIGURE 11. — Development of mouse follicle/oocyte culture systems. Culture systems to support different stages of mouse oocytes through meiotic maturation, fertilization to the production of live young have been developed, initially starting with in vitro maturation of oocytes from antral stages (531), leading to successful fertilization and live young (532). Progressively moving to in vitro growth (IVG) of preantral follicles (533, 534) and now IVG of primordial follicles (535). IVF, in vitro fertilization. Image created with BioRender.com, with permission.