Associations between 14 modifiable factors and incident cardiovascular disease in overall, middle-aged (38 to <50 years), quinquagenarian (50 to <60 years) and the elderly (≥60 years) groups. Models were adjusted for age, sex, ethnicity, region, family history, and mutually adjusted for individual risk factors. P for interaction was estimated with the use of likelihood ratio test. P values were false discovery rate (FDR) corrected. Abbreviations: HR, hazard ratios; HDL, high-density lipoprotein; SEP, socioeconomic and psychosocial risk factors; PM2.5, fine particulate matter with diameter <2.5 μm.