Figure 1.

Overall design and construction of TIGER

TIGER aims to help researchers unearth potential mechanisms in anti-tumor immunity and discover potential biomarkers by integrating tumor immunology-related bulk transcriptome, single-cell transcriptome, and immune screening data. TIGER provides four functional analysis modules, including single-cell immunity, immunotherapy response, response signature, and immune screening, to allow users to access the resources in TIGER. TIGER, tumor immunotherapy gene expression resource; RNA-seq, RNA sequencing; scRNA-seq, single-cell RNA sequencing; AUC, area under the curve; FC, fold change; FPKM, fragments per kilobase of transcript per million.