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. 2023 Oct 10;18(3):225–248. doi: 10.5114/pg.2023.131998

Table VI.

First-line treatment in H. pylori eradication

Regime Dosage Treatment duration
Quadruple therapy with bismuth • PPIa BID
• Bismuth 120 mg QID
• Metronidazole 500 mg TID or QID
• Tetracycline 500 mg TID or QID
10–14 days
Quadruple therapy without bismuth • PPIa BID
• Amoxicillin 1000 mg BID
• Metronidazole 500 mg BID
• Clarithromycin 500 mg BID
14 days
a

Standard proton pump inhibitor (PPI) doses: omeprazole 20 mg, esomeprazole 20 mg, rabeprazole 20 mg, lansoprazole 30 mg, pantoprazole 40 mg.