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. 2023 Oct 10;18(3):225–248. doi: 10.5114/pg.2023.131998
Poland belongs to countries with a high rate of clarithromycin resistance (> 15%), therefore the recommended first-line treatment in Poland is quadruple therapy with bismuth (PPI, bismuth, tetracycline, nitroimidazole) or quadruple therapy without bismuth (PPI, amoxicillin, clarithromycin, nitroimidazole), given their high effectiveness and lower complexity compared to sequential or hybrid treatment.
Quality of evidence: moderate. Recommendation: strong.