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. 2023 Oct 16;24(11):e56845. doi: 10.15252/embr.202356845

Figure EV5. Embryos and newborn pups from mothers fed a normal or ketogenic diet.

Figure EV5

  • A–C
    E8.5 (A), E10.5 (B), and E15.5 (C) embryos from mothers fed a normal or ketogenic diet.
  • D
    Gonads in E15.5 embryos from mothers fed a normal or ketogenic diet.
  • E
    P1 pups from mothers fed a normal or ketogenic diet. Weight was measured (normal, n = 25; ketogenic, n = 21).
  • F
    Gonads in P1 pups, testes (normal, n = 14; ketogenic, n = 8), ovaries (normal, n = 9; ketogenic, n = 8). Gonad size was measured as the area value of each gonad quantified in Image J.
  • G
    Weight of P2 pups from mothers fed a normal or ketogenic diet until E15.5 and normal diet afterwards (normal, n = 12; ketogenic, n = 13).
  • H
    Gonads in P2 pups after switching to a normal diet at E15.5, testes (normal, n = 6; ketogenic, n = 8), ovaries (normal, n = 8; ketogenic, n = 8). Gonad size was measured as the area value of each gonad quantified in ImageJ.

Data information: Values are plotted as mean ± SE. *P < 0.05, **** P < 0.0001 (Student's t‐test). Scale bar: 500 μm (A, B, ovaries in D, F, and H), 5 mm (C), 1 mm (testes in D, F, and H), 1 cm (E).