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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Tuberculosis (Edinb). 2022 Oct 4;137:102269. doi: 10.1016/j.tube.2022.102269

Fig. 1. Effect of incubation temperature and time on omadacycline potency.

Fig. 1.

(A) Omadacycline concentrations versus time were modeled using an exponential decline model to identify the half-life of decay under the two different conditions. The concentration of drug solution was observed to be reduced by ~50% in the first 24hrs. (B) Results shown are % reduction in methicillin-resistant Staphylococcus aureus (MRSA) incubated with freshly prepared omadacycline at 0.5mg/L and the same omadacycline preparation after incubation at 37°C. Microbial kill was reduced by 66.45 + 19.38% over the 24hrs.