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Inhibitory sigmoid Emax model for M. kansasii burden versus omadacycline concentration after 7 days of incubation.
| Parameter | No Supplementation |
50% Daily Drug Supplementation |
|---|---|---|
| Estimate (95% confidence intervals) | Estimate (95% confidence intervals) | |
|
| ||
| Econ (log10 CFU/mL) | 7.07 (6.72–7.54) | 6.08 (5.65–6.58) |
| Emax (log10 CFU/mL) | 5.70 (3.21 to imprecise) | 6.97 (5.81–9.76) |
| H | 0.83 (Imprecise to 1.68) | 1.05 (0.68–1.68) |
| EC50 (mg/L] | 63.39 (18.50 to imprecise) | 14.79 (9.44–39.22) |
| R 2 | 0.93 | 0.98 |
