Table 1.
General characteristics of the patients in the study
| Characteristic | Total (140) | Non-COVID-19 (n = 61) |
COVID-19 (n = 79) | p |
|---|---|---|---|---|
|
Sex a Male Female |
96 (68.6) 44 (31.4) |
34 (55.7) 27 (44.3) |
62 (78.5) 17 (21.5) |
< 0.01 |
| Age b | 67.5 (25–97) | 72 (25–97) | 64 (32–89) | 0.03 |
| Weight (kg) | 76 (36–130) | 70 (36–130) | 80 (44–127) | < 0.01 |
| BMI (kg/m2) b | 26.34 (13–43) | 24.56 (13–43) | 27.34 (18–43) | ˂0.01 |
|
Comorbidities a Diabetes Systemic Hypertension COPD Heart Failure Ischemic Heart Disease |
31 (22.1) 71 (50.7) 10 (7.1) 7 (5) 12 (8.6) |
8 (13.1) 28 (45.9) 8 (13.1) 4 (6.6) 5 (8.2) |
23 (29.1) 43 (54.4) 2 (2.5) 3 (3.8) 7 (8.9) |
0.02 0.31 0.01 0.45 0.88 |
| SAPS-II score b | 33 (6–89) | 32 (6–70) | 36 (10–89) | 0.07 |
| APACHE-II score b | 14 (0–38) | 13 (0–30) | 14 (5–38) | 0.68 |
| SOFA score b | 7 (0–90) | 5 (0–9) | 8 (2–18) | 0.01 |
| PaO2/FiO2 | 163 (133–226) | 185 (135–229) | 158 (109–221) | 0.10 |
|
ARDS classification a Mild Moderate Severe |
52 (37.1) 71 (50.7) 17 (12.1) |
25 (40.9) 33 (54) 3 (4.9) |
27 (34.1) 38 (48.1) 14 (17.7) |
0.06 |
| RV failure a | 9 (6.4) | 4 (6.6) | 5 (6.3) | 0.95 |
| Mechanical Ventilation a | 100 (71.4) | 22 (36.1) | 78 (98.7) | ˂0.01 |
| Renal Replacement Therapy a | 16 (11.4) | 3 (4.9) | 13 (16.5) | 0.02 |
| ECMO a | 1 (0.7) | 0 | 1 (1.3) | 0.37 |
| Duration Mechanical Ventilation b | 6 (0–64) | 0.88 (0–18) | 13 (0–64) | ˂0.01 |
| Days in Critical Care Unit b | 9.5 (0–68) | 2 (0–30) | 17 (1–68) | ˂0.01 |
| In-Hospital stay b | 13.5 (1–68) | 6 (1–31) | 22 (1–68) | ˂0.01 |
| Deaths a | 45 (32.1) | 12 (19.7) | 33 (41.8) | ˂0.01 |
Data presented as: a total of patients (%), b median (interquartile range). Abbreviations: BMI: body mass index, SAPS-II: Simplified Acute Physiology Score II, APACHE-II: Acute Physiology and Chronic Health Evaluation II score, SOFA: Sequential Organ Assessment score, COPD: Chronic Obstructive pulmonary disease, RV: right ventricular, ECMO: Extracorporeal membrane oxygenation. Statistical analysis: U Mann-Whitney test was performed for numeric variables, and Chi square test was used for nominal/ordinal variables