Table 5.
Subanalysis of mortality in DENV-2-infected patients
| Demographic Characteristicsa | Survived | Death | P value | Logistic regression | |
|---|---|---|---|---|---|
| n = 1460 | n = 48 | P value | OR (95% CI) | ||
| Age (Years) | 51 (0–91) | 74 (48–88) | < 0.001 | 0.18 | 1.044 (0.980–1.113) |
| 0–59 | 941 (64.5%) | 6 (12.5%) | < 0.001 | 0.77 | 0.777 (0.144–4.202) |
| ≥60 | 519 (35.5%) | 42 (87.5%) | |||
| Sex | |||||
| Male | 752 (51.5%) | 17 (35.4%) | 0.028 | 0.027 | 3.294 (1.145–9.474) |
| Female | 708 (48.5%) | 31 (64.6%) | |||
| Severity | |||||
| Dengue fever | 1395 (95.5%) | 10 (20.8%) | < 0.001 | < 0.001 | 92.141 (30.775–275.874) |
| Severe dengue | 65 (4.5%) | 38 (79.2%) | |||
| Chronic diseaseb | |||||
| Diabetes mellitus | 144 (10.3%) | 14 (46.7%) | < 0.001 | 0.661 | 1.331 (0.370–4.782) |
| Hypertension | 229 (16.3%) | 15 (50.0%) | < 0.001 | 0.323 | 0.563 (0.181–1.757) |
| Congestive heart failure | 25 (1.8%) | 4 (13.3%) | < 0.001 | 0.111 | 4.048 (0.725–22.607) |
| COPD | 58 (4.1%) | 6 (20.0%) | < 0.001 | 0.461 | 1.705 (0.413–7.042) |
| Cerebrovascular disease | 60 (4.3%) | 3 (10.0%) | 0.131 | ||
| Moderate to severe CKD | 18 (1.3%) | 3 (10.0%) | < 0.001 | 0.796 | 0.789 (0.130–4.791) |
| Charlson comorbidity index scoreb | 1 (0–10) | 5 (1–8) | < 0.001 | 0.293 | 1.276 (0.810–2010) |
aPresented as the numbers (%) except for average age and CCI score, which are shown as the median (range). The days PSO of these patients were ≤ 6 days. We excluded four patients from this analysis who did not die from severe dengue
bN = 1,432, survival = 1,402, death = 30. COPD Chronic obstructive pulmonary disease, CKD Chronic kidney disease