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. 2023 Nov 6;13:200. doi: 10.1186/s13578-023-01151-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — MiR-181a expression is high in Olaparib resistance TNBC cell lines. A Volcano plot showing the miR changes between parental and olaparib-resistant (OlaR) HCC1937 TNBC cell line using HTGq miR WTA. B Quantification of miR-181a, miR-181b, miR-181c, and miR-181d levels (counts per million, CPM) by HTG miR WTA in parental and OlaR HCC1937 cell line (Student’s t-test). C Quantification of miR-181a levels RT-qPCR (C) in parental and OlaR HCC1937 cell line (Student’s t-test). D MiR-181a levels in tumor-adjacent normal breast (Adj. Normal) and primary BC (Primary) tissues in the TCGA BRCA database (Mann–Whitney test). E MiR-181a levels in tissues from the tumor-adjacent normal breast (Adj. Normal), Luminal (Lum), Luminal-HER2 (Lum-HER2), HER2, and TNBC in the TCGA BRCA dataset (One-way ANOVA and Tukey’s multiple comparisons test). F MiR-181a levels in tissues from the tumor-adjacent normal breast (Adj. Normal), Normal-like (Norm-like), Luminal-A (LumA), Luminal-B (LumB), HER2-enriched, and basal-like breast cancer (BLBC) in the TCGA BRCA dataset (One-way ANOVA and Tukey’s multiple comparisons test). G Overall survival (OS) analysis for TNBC patients in the TCGA BRCA dataset (Log-rank test)