Figure 2.

Circulating, extracellular vesicle-packed miRNA expression signature of the DCO group at four timepoints after trauma: 1.5, 2.5, 24, and 72 h.. All depicted miRNAs were significantly deregulated at the respective timepoint. A maximum of 10 up- and downregulated miRNAs are shown. Fold regulation (FR) was calculated using comparative 2^−ΔΔCt method, in which a downregulation was represented as the negative inverse of the acquired 2^−ΔΔCt value.