Figure 5.

miRNA targeted mRNAs are deregulated in lung tissue, depending on the applied surgical treatment strategy: intramedullary nailing (Early-Total-Care) versus external fixation (Damage-Control-Orthopaedics). Black dotted line displays the threshold of a fold regulation of |≥ 2| above or below which a mRNA was considered significantly deregulated. Significant differences in mRNA expression between the same sample types from different treatment groups are marked as follows: ****p-value<0.0001. Error bars depict standard error of the mean.