Table 1. Histopathology Changes Caused by Membranous Nephropathy.

Microscopy → Stage ↓	LM	IF	EM
Stage 1	Normal GCL	IgG fine granular in GCL	Subepithelial electron-dense deposits
Stage 2	Thick GCL with GBM spikes (MSS)	IgG granular in GCL	Subepithelial electron-dense deposits with spikes
Stage 3	Thick GCL and with chain links (MSS)	IgG granular in GCL	Subepithelial electron-dense deposits involved by the GBM
Stage 4	Thick GCL with variable changes (MSS)	IgG granular and GCL variable	GBM with variable irregularities

LM: light microscopy; IF: immunofluorescence microscopy; EM: electron microscopy; GCL: glomerular capillary loop; MSS: methenamine silver stain; GBM: glomerular basement membrane.