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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Nat Struct Mol Biol. 2023 May 25;30(6):824–833. doi: 10.1038/s41594-023-00991-z

Extended Data Fig. 6. TSEN54 is the anchor that mediates the interaction of CLP1 with the TSEN complex.

Extended Data Fig. 6

Overexpression (in HEK cells) and immunoprecipitations of the individual TSEN proteins (lanes 1–4 and lanes 7–10) or full TSEN complex (lanes 5 and 11) in the absence (lanes 1–5) and presence (lanes 7–11) of CLP1 reveals strong association between CLP1 and TSEN54 (lane 10) as well as the full TSEN complex (lane 11). The experiments were conducted as previously reported1 using CLP1-TEV-GFP.