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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Nat Struct Mol Biol. 2023 May 25;30(6):824–833. doi: 10.1038/s41594-023-00991-z

Fig. 3 |. Structure of the pre-tRNA reveals a familiar architecture to mature tRNA.

Fig. 3 |

2D and 3D structures of a. unmodified mature tRNA-PHE (PDBID: 3L0U) and b. intron containing pre-tRNA-ARG structure, with the acceptor stem (blue), D-Arm (lime green), anticodon stem loop (dark grey), anticodon (teal), intron (red), variable loop (purple) and TψC-Arm (yellow) labeled. The cut sites for TSEN2 (orange) and TSEN34 (pink) are labelled on the pre-tRNA 2D structure. c. Electron density map around the pre-tRNA, with the pre-tRNA structure docked into the density map.