Table 1.
Clinical and angiographic characteristics in patients with and without residual ischemia
| Total (N = 1170) | Residual ischemia group (n = 155) | No residual ischemia group (n = 1015) | |
|---|---|---|---|
| Age, years | 60.8 ± 10.2 | 62.1 ± 10.4 | 60.6 ± 10.2 |
| Sex | |||
| Men | 930 (79.5) | 120 (77.4) | 810 (79.8) |
| Women | 240 (20.5) | 35 (22.6) | 205 (20.2) |
| Body mass index, kg/m2 | 25.7 ± 3.0 | 25.2 ± 3.1 | 25.8 ± 3.0 |
| Hypertension | 722 (61.7) | 101 (65.2) | 621 (61.2) |
| Diabetes mellitus | 362 (30.9) | 61 (39.4) | 301 (29.7) |
| Hypercholesterolemia | 812 (69.4) | 119 (76.8) | 693 (68.3) |
| Current smoking | 317 (27.1) | 38 (24.5) | 279 (27.5) |
| Family history of CAD | 233 (19.9) | 28 (18.1) | 205 (20.2) |
| Previous myocardial infarction | 277 (23.7) | 49 (31.6) | 228 (22.5) |
| Previous PCI | 284 (24.3) | 41 (26.5) | 243 (23.9) |
| Previous stroke | 157 (13.4) | 20 (12.9) | 137 (13.5) |
| Peripheral artery disease | 106 (9.1) | 19 (12.3) | 87 (8.6) |
| Chronic kidney disease | 200 (17.1) | 26 (16.8) | 174 (17.1) |
| Clinical presentation | |||
| Silent ischemia | 118 (10.1) | 20 (12.9) | 98 (9.7) |
| Stable angina | 464 (39.7) | 59 (38.1) | 405 (39.9) |
| Unstable angina | 541 (46.2) | 68 (43.9) | 473 (46.6) |
| NSTEMI | 25 (2.1) | 4 (2.6) | 21 (2.1) |
| STEMI | 22 (1.9) | 4 (2.6) | 18 (1.8) |
| Left ventricular ejection fraction, % | 63.1 ± 7.2 | 61.2 ± 8.6 | 63.4 ± 7.0 |
| <45 | 38 (3.2) | 11 (7.1) | 27 (2.7) |
| Number of non-LM diseased vessels | |||
| 0 | 157 (13.4) | 13 (8.4) | 144 (14.2) |
| 1 | 349 (29.8) | 48 (31.0) | 301 (29.7) |
| 2 | 512 (43.8) | 57 (35.8) | 455 (44.8) |
| 3 | 152 (13.0) | 37 (23.9) | 115 (11.3) |
| LM lesion type | |||
| De novo | 1138 (97.3) | 148 (95.5) | 990 (97.5) |
| Restenosis | 32 (2.7) | 7 (4.5) | 25 (2.5) |
| Medina | |||
| 1,1,1 | 163 (13.9) | 18 (11.6) | 145 (14.3) |
| 1,0,1 | 43 (3.7) | 7 (4.5) | 36 (3.5) |
| 1,1,0 | 583 (49.8) | 91 (58.7) | 492 (48.5) |
| 1,0,0 | 264 (22.6) | 26 (16.8) | 238 (23.4) |
| 0,1,1 | 117 (10.0) | 13 (8.4) | 104 (10.2) |
| True LM bifurcation | 323 (27.6) | 38 (24.5) | 285 (28.1) |
| DEFINITION criteria | |||
| Complex LM bifurcation | 113 (40.4) | 10 (32.3) | 103 (41.4) |
| Simple LM bifurcation | 167 (59.6) | 21 (67.7) | 146 (58.6) |
| LM moderate-to-severe calcification | 217 (18.5) | 36 (23.2) | 181 (17.8) |
| LM thrombus-containing lesions | 4 (0.3) | 0 (0) | 4 (0.4) |
| LM total occlusion | 30 (2.6) | 4 (2.6) | 26 (2.6) |
| Anatomic SYNTAX score | 22.9 ± 6.9 | 25.4 ± 7.4 | 22.5 ± 6.7 |
| Low (≤22) | 613 (52.4) | 58 (37.4) | 555 (54.7) |
| Intermediate (23–32) | 454 (38.8) | 74 (47.7) | 380 (37.4) |
| High (≥33) | 103 (8.8) | 23 (14.8) | 80 (7.9) |
| Pre-PCI physiology assessment | |||
| Pre-PCI LAD μQFR | 0.64 ± 0.24 | 0.62 ± 0.22 | 0.65 ± 0.24 |
| Pre-PCI LCX μQFR | 0.75 ± 0.21 | 0.65 ± 0.24 | 0.77 ± 0.21 |
Data are mean (SD), n (%), median (IQR), or n/N (%).
CAD, coronary artery disease; LAD, left anterior descending; LCX, left circumflex artery; LM, left main; NSTEMI, non-ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; SYNTAX, SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery; μQFR, Murray law-based quantitative flow ratio.