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. 2023 May 16;44(41):4324–4336. doi: 10.1093/eurheartj/ehad318

Table 3.

Univariable and multivariable predictors of residual ischemia

Univariable analysis Multivariable analysis
OR (95% CI) P-value OR (95% CI) P-value
Model 1: baseline variables
 Age 1.01 (1.00–1.03) 0.09 1.01 (0.99–1.03) 0.36
 Male 0.87 (0.58–1.30) 0.49 0.98 (0.63–1.53) 0.94
 Diabetes 1.54 (1.09–2.18) 0.02 1.44 (1.00–2.08) 0.051
 Previous myocardial infarction 1.60 (1.10–2.31) 0.01 1.31 (0.87–1.98) 0.20
 LVEF, per 10% decrease 1.43 (1.15–1.78) 0.001 1.30 (1.02–1.67) 0.03
 Multi-vessel disease 1.20 (0.85–1.70) 0.29 1.08 (0.75–1.57) 0.67
 True LM bifurcation 1.20 (0.81–1.78) 0.36 1.79 (1.15–2.80) 0.01
 LM moderate-to-severe calcification 1.39 (0.93–2.09) 0.11 1.34 (0.87–2.07) 0.19
 Pre-PCI LM-LAD RVD (per 0.1 decrease) 1.02 (0.99–1.05) 0.24 0.98 (0.95–1.02) 0.28
 Pre-PCI LM-LAD %DS (per 10% increase) 1.08 (0.98–1.19) 0.14 0.98 (0.88–1.09) 0.68
 Pre-PCI LCX RVD (per 0.1 decrease) 1.05 (1.02–1.08) 0.001 1.05 (1.02–1.09) 0.04
 Pre-PCI LCX %DS (per 10% increase) 0.98 (0.91–1.06) 0.68 0.94 (0.86–1.02) 0.13
 Anatomic SYNTAX score (per 1 increase) 1.06 (1.03–1.08) <0.0001 1.06 (1.03–1.08) <0.0001
 Pre-PCI LAD μQFR (per 0.1 decrease) 1.77 (0.88–3.56) 0.11 0.96 (0.88–1.04) 0.29
 Pre-PCI LCX μQFR (per 0.1 decrease) 1.23 (1.15–1.32) <0.0001 1.28 (1.18–1.39) <0.0001
Model 2: procedural variables
 IVUS guidance 0.74 (0.53–1.04) 0.08 0.95 (0.66–1.37) 0.79
 Total number of stents per LM lesion 0.92 (0.74–1.16) 0.49 0.99 (0.78–1.26) 0.94
 Provisional one-stent crossover technique 2.91 (1.75–4.85) <0.0001 2.03 (1.12–3.70) 0.02
 POT performed 1.32 (0.94–1.86) 0.11 0.97 (0.66–1.42) 0.87
 Final kissing balloon inflation 0.51 (0.36–0.73) 0.0002 0.69 (0.46–1.03) 0.07
 Post-dilation performed 0.94 (0.54–1.64) 0.82 1.22 (0.66–2.26) 0.53
 Post-PCI LM-LAD %DS (per 10% increase) 1.06 (0.72–1.55) 0.77 1.04 (0.69–1.55) 0.86
 Post-PCI LCX %DS (per 10% increase) 1.26 (1.14–1.38) <0.0001 1.18 (1.07–1.30) 0.001
 Residual SYNTAX score (per 1 increase) 1.11 (1.08–1.14) <0.0001 1.10 (1.07–1.14) <0.0001

DS, diameter stenosis; OR, odds ratio; RVD, reference vessel diameter; other abbreviations as in Tables 1 and 2.