Comparison 3. radical radiotherapy vs radical radiotherapy + chemotherapy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 survival	25	3033	Peto Odds Ratio (95% CI)	0.90 [0.83, 0.97]
1.1 long term alkylating agent	7	665	Peto Odds Ratio (95% CI)	0.98 [0.83, 1.16]
1.2 vinca alkaloids / etoposide	3	349	Peto Odds Ratio (95% CI)	0.87 [0.70, 1.09]
1.3 other drugs	3	239	Peto Odds Ratio (95% CI)	0.98 [0.74, 1.29]
1.4 cisplatin based	12	1780	Peto Odds Ratio (95% CI)	0.87 [0.79, 0.96]
2 subgroup for survival ‐ age	4		Peto Odds Ratio (95% CI)	Totals not selected
3 subgroup for survival ‐ sex	2		Peto Odds Ratio (95% CI)	Totals not selected
4 subgroup for survival ‐ performance status	2		Peto Odds Ratio (95% CI)	Totals not selected
5 subgroup for survival ‐ histology	3		Peto Odds Ratio (95% CI)	Totals not selected
6 subgroup for survival ‐ stage	2		Peto Odds Ratio (95% CI)	Totals not selected