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| Methods | RCT ‐ 1980‐84 | |
| Participants | 52 patients | |
| Interventions | radical radiotherapy vs radical radiotherapy + chemotherapy doxorubicin 40 lomustine* 30 cyclophosphamide 400 methotrexate 30 | |
| Outcomes | survival | |
| Notes | chemotherapy given until tumour progression or toxicity radiotherapy 55 Gy in 25 fractions** | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment (selection bias) | Low risk | A ‐ Adequate |
