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. 2000 Apr 24;2000(2):CD002139. doi: 10.1002/14651858.CD002139

c25 SWOG 8300 b.

Methods RCT ‐ 1984‐88
Participants 126 patients
Interventions radical radiotherapy vs radical radiotherapy + chemotherapy
 fluorouracil 1200
 vincristine 2
 mitomycin C 10
 cisplatin 40
 doxorubicin 40
 cyclophosphamide 400
Outcomes survival
Notes unpublished
 6 cycles of chemotherapy, 2 given before radiotherapy
 radiotherapy 58 Gy in 29 fractions
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk A ‐ Adequate