Supplementary Table 4. Clinical characteristics depending on the serum phosphate excursions among patients with CVCS.

	All (n= 18)	0 time (n= 4)	3 times (n= 14)	p
Age (year)	70.0±9.2	78.3±6.7	67.6±8.5	0.018
Male (%)	15 (83.3)	4 (100.0)	11 (78.6)	0.446
Smoking (%)	11 (61.1)	3 (75.0)	8 (57.1)	0.485
HT (%)	18 (100.0)	4 (100.0)	14 (100.0)	-
DM (%)	8 (44.4)	2 (50.0)	6 (42.9)	0.618
DLp (%)	7 (38.9)	0 (0.0)	7 (50.0)	0.108
SBP (mmHg)	145.7±20.3	144.3±20.9	146.1±20.9	0.875
DBP (mmHg)	67.6±10.2	66.8±6.7	67.8±11.2	0.864
ACE-I/ARB (%)	11 (61.1)	2 (50.0)	9 (64.3)	0.515
Statin (%)	12 (66.7)	2 (50.0)	10 (71.4)	0.407
Lanthanum carbonate (%)	10 (55.6)	2 (50.0)	8 (57.1)	0.618
Calcium carbonate (%)	8 (44.4)	2 (50.0)	6 (42.9)	0.618
Sevelamer (%)	0 (0.0)	0 (0.0)	0 (0.0)	-
Bixalomer (%)	0 (0.0)	0 (0.0)	0 (0.0)	-
Vitamin D (%)	7 (38.9)	2 (50.0)	5 (35.7)	0.515
Warfarin (%)	2 (11.1)	1 (25.0)	1 (7.1)	0.405
Hb (g/dL)	9.0±1.1	9.2±0.8	8.9±1.3	0.705
cCa (mg/dL)	8.6±0.4	8.3±0.2	8.7±0.4	0.053
P (mg/dL)	5.7±1.2	4.3±1.1	6.1±1.0	0.005
Albumin (g/dL)	3.4±0.5	3.4±0.4	3.4±0.5	0.979
Intact PTH (pg/mL)	235.0 (158.8 – 335.0)	161.0 (36.8 – 484.8)	239.0 (179.0 – 335.0)	0.442
CACS	510.1 (139.4 – 1122.0)	821.4 (219.1 – 1927.3)	495.8 (104.5 – 1058.7)	0.327
CVCS	2.0 (0.0 – 2.25)	1.0 (0.0 – 2.75)	2.0 (0.0 – 2.25)	0.721

AUC, area under the curve; HT, hypertension; DM, diabetes mellitus; DLp, dyslipidemia; SBP, systolic blood pressure; DBP, diastolic blood pressure; ACE-I, angiotensin-converting enzyme inhibitor; ARB, angiotensin II type 1 receptor blocker; Hb, hemoglobin; cCa, corrected calcium; P, phosphate; PTH, parathyroid hormone; CACS, coronary artery calcium score; CVCS, cardiac valvular calcification score.

Values are presented as mean±SD or median (interquartile range).