Table 2.

Tumor response by investigator review per RECIST v1.1.

	Total n = 59 No. (%)	Cohort A n = 31 No. (%)	Cohort B n = 28 No. (%)
Best overall response
Complete response	0 (0.0)	0 (0.0)	0 (0.0)
Partial response	21 (35.6)	11 (35.5)	10 (35.7)
Stable disease	33 (55.9)	17 (54.8)	16 (57.1)
Progressive disease	4 (6.8)	3 (9.7)	1 (3.6)
Not evaluable	0 (0.0)	0 (0.0)	0 (0.0)
Not applicable	1 (1.7)	0 (0.0)	1 (3.6)
Objective response	21 (35.6)	11 (35.5)	10 (35.7)
95% CI	23.6, 49.1	19.2, 54.6	18.6, 55.9
Disease control	54 (91.5)	28 (90.3)	26 (92.9)
95% CI	81.3, 97.2	74.2, 98.0	76.5, 99.1
Median time to response, months	1.61	2.76	1.4
Min-Max	1.3–8.3	1.3–8.3	1.3–6.9
Median duration of response, months	13.6	13.6	13.67
95% CI	5.55, NE	4.14, NE	3.52, NE