Extended Data Fig. 5. TB outcome by tissue compartment.
a-e) Lung pathology (a), thoracic lymph node (LN) pathology (b), extrapulmonary pathology (c), lung Mtb burden (d), and thoracic LN Mtb burden (e) at necropsy. Each point indicates an individual animal and horizontal bars indicate group medians (Unvax, n = 8; IV BCG, n = 7; SIV/Unvax, n = 11; SIV/IV BCG, n = 12). Kruskal Wallis tests were performed with Dunn’s multiple comparisons between SIV-naïve, vaccinated and unvaccinated groups (dark blue circles and light blue squares, respectively); and SIV+, vaccinated and unvaccinated groups (red, up-pointing triangle and gold, down-pointing triangle, respectively). P-values are shown. All statistical tests were two-sided.