Fig. 5. Mycobacterial-specific antibodies in plasma and BALF following BCG vaccination.
a–f, Antibodies specific for H37Rv whole cell lysate were assessed by ELISA for both vaccinated groups: plasma IgG (a), BALF IgG (b), plasma IgA (c), BALF IgA (d), plasma IgM (e) and BALF IgM (f). AUC was determined by calculating the area under the dilution series curve using GraphPad Prism. Individual animals indicated by symbols for IV BCG (light-blue square; n = 7) and SIV/IV BCG (gold, down-pointing triangle; n = 12). Wilcoxon paired signed rank tests were performed to determine significance. P values are shown.