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. 2023 Oct 28;146(6):803–815. doi: 10.1007/s00401-023-02646-1

Table 1.

Clinical histories of initial prospective IPV case series per available data

Case Age (decade) Ethnicity Prior TBI Nonfatal strangulation Epilepsy Mental health disorder Other medical conditions Cause and manner of death Postmortem family interview
NY1 3rd H

Cause: Blunt force trauma of the head

Manner: Homicide

NY2 3rd B HIV/AIDS; COVID–19

Cause: COVID–19

Manner: Natural

 + 
NY3 3rd W  +  SUD Asthma; pregnancy

Cause: Acute intoxication by the combined effects of fentanyl, heroin, and cocaine

Manner: Accident (substance use)

 + 
NY4 4th H  +  AUD; SUD; depression; anxiety disorder; ADHD Graves’ disease, s/p radiotherapy, with hypothyroidism

Cause: Positional asphyxia due to lodgment and suspension within garbage chute complicating acute intoxication by the combined effects of cocaine and ethanol

Manner: Accident

NY5 4th H HIV/AIDS; prior meningitis; pregnancy

Cause: Multiple blunt trauma

Manner: Undetermined

NY6 4th H  +   +  AUD; SUD Asthma

Cause: Acute fentanyl intoxication

Manner: Accident (substance use)

 + 
NY7 4th B  +   +   +  AUD

Cause: Homicidal asphyxia including compression of neck

Manner: Homicide

NY8 4th H  +   +   +  SUD; bipolar disorder

Cause: Asphyxia including neck and chest compression

Manner: Homicide

NY9 5th H  +  AUD; anxiety disorder Asthma; COVID–19

Cause: Undetermined

Manner: Undetermined

NY10 5th B SUD; bipolar disorder HIV/AIDS; hypertension; CAD; asthma

Cause: Probable viral meningoencephalitis

Manner: Natural

NY11 6th W  +  SUD; anxiety disorder HIV/AIDS; hypertension; CHD; pacemaker

Cause: Complications of acute intoxication including methadone

Manner: Accident (substance use)

NY12 6th H  +  Hypertension; Hepatitis C; DM; AVR; pacemaker

Cause: Complications of chronic and acute substance use including cocaine

Manner: Accident (substance use)

NY13 7th H  +   +  AUD; depression DM; HLD

Cause: Chronic alcohol use

Manner: Natural

NY14 8th B  +   +  Depression Remote temporal lobectomy for post–traumatic epilepsy; hypertension; pacemaker; “memory loss”

Cause: Hypertensive and atherosclerotic cardiovascular disease

Manner: Natural

Data were obtained from available medical records, scene investigations, and/or next-of-kin. Data reported herein do not reflect objective postmortem findings; see Table 2 for postmortem data. See Supplement for details of findings in archival cohorts

 +  assessed and present, – assessed and evidence not found, ADHD attention deficit-hyperactivity disorder, AUD alcohol use disorder, AVR aortic valve replacement, B Black, CAD coronary artery disease, CHD congenital heart disease, DM diabetes mellitus, H Hispanic/Latina, HIV/AIDS human immunodeficiency virus/acquired immune deficiency syndrome, HLD hyperlipidemia, NY# from New York City Office of Chief Medical Examiner, SUD substance use disorder, W White

See text for further explanation and definitions used