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. 2023 Oct 24;17:1253438. doi: 10.3389/fncel.2023.1253438

Table 1.

Effect of acupuncture on the repair of peripheral nerve injury.

Study Model Acupoints Acupuncture type/parameter Major effects
Hoang et al. (2012) Sciatic nerve crush GB30, GB34 EA/0.8–1 mA, 2 Hz, 15 min motor recovery↑, target re-innervation pain↓
Ho et al. (2013) Transected Median Nerve PC7, PC3 EA/1 mA, 2 Hz, 15 min Electrophysiological Measurements (Latency, amplitude, MAPs, NCV)↑, Morphologically (axon number, endoneurial area, total nerve area, blood vessel number)↑, Functionally (Grasping Test)↑
Cheng et al. (2001) Rat sciatic nerve GB30, GB34 EA/0.8-1 mA, 2 Hz, 15 min axon density↑, blood vessel area↑, percentage of blood vessel area↑
Li H. et al. (2021) Upper limb peripheral nerve injury C6-T1 Jiaji points EA/once a day, 30 min Barthel index↑, Fugl-Meyer assessment score↑, motor nerve conduction velocity↑, sensory nerve conduction velocity and amplitude↑, SF-36↑
Napadow et al. (2007a,b) CTS Common:TW-5, PC-7 matching aupoint: HT-3, PC-3, SI-4, LI-5, LI-10, LU-5 EA/2 Hz, 10 min BCTSQ ↑, nerve sensory latencies ↑, grip strength↑, fMRI: inducing beneficial cortical plasticity manifested ↑
Inoue et al. (2011) Peripheral nerve damage Anode electrode–proximal to the injured part, cathode electrode–innervated muscle DCEA/100 Hz, 20 min functional↑: neurapraxia 2, axonotmesis 3; No functional: axonotmesis 1, neuromesis 1
Ho et al. (2014) CTS PC7, PC6 EA/0.8 mA, 2 Hz, 15 min Elec-Acu group: short clinical questionnaire by Lo and Chiang↑; Acu group: grip strength↑, distal median motor amplitude of the palm-wrist segment↑, Tinel’s sign↓; No changes: two-point discrimination
Yang et al. (2011) CTS PC-7, PC-6 MA/30 min modified GSS↑, DML↑, CMAP↑, MNCV↑, DSL↑, SNAP↑, W-P SNCV↑
Fan and Wu (2015) Acute lumbar muscle sprain Bilateral SI-3, Jiaji (EX-B2), Ashi points EA/10-25 Hz, 20 min FDVs of the bilateral lumbar muscle↑, temperature index of the lumbar skin↑

MAPs, muscle action potentials; NCV, nerve conduction velocity; CTS, carpal tunnel syndrome; BCTSQ, Boston Carpal Tunnel Syndrome Questionnaire; GSS, Global symptom score; DML, distal motor latency; CMAP, compound muscle action potential; MNCV, motor nerve conduction velocity; DSL, distal sensory latency; SNAP, sensory nerve action potential; W-P SNCV, wrist-palm sensory nerve conduction velocity; FDV, force-displacement value.