Fig. 4.

Explained excess risk of ASCVD in diabetes by remnant cholesterol, LDL-cholesterol and low-grade inflammation in the Copenhagen General Population Study. Excess risk of ASCVD and its components peripheral artery disease, myocardial infarction and ischaemic stroke in individuals with diabetes could be partly explained by elevated remnant cholesterol and low-grade inflammation measured as elevated high-sensitivity C-reactive protein, but not by elevated LDL-cholesterol. LDL-cholesterol was lower in individuals with diabetes than in individuals without diabetes and could therefore not explain excess risk. Results are from Cox regressions adjusted for age, sex, smoking status, cumulative smoking and birth year. The Bonferroni-corrected threshold equivalent to p=0.05 is 0.05/12= 0.0042 due to 12 statistical tests. NA, not applicable