Skip to main content
. 2023 Nov 6;34(11):56. doi: 10.1007/s10856-023-06757-9

Table 2.

Effect of XL-HA (batch 1) concentration on the dynamic viscoelastic properties and TA removal ability

Sample Removal Solidity Liquidity Behavior 5 min after injection into BSS
Abilitya (%) S-index (min) Tweezers operation L-index (min) Injectabilityb
1% HA300 0 Not tried Impossible Fluid Easy Diffusive
1% HA-AEA 0 Not tried Impossible Fluid Easy Diffusive
1% HA-DBCO 0 Not tried Impossible Fluid Easy Diffusive
0.13% XL-HA 7 Not tried Impossible Fluid Easy Diffusive
0.65% XL-HA Not tried 10.3 Breakable 8.3 Easy Non-dispersive
0.76% XL-HAd 55 Stretchable, breakable Easy
0.86% XL-HA 45 5.4 Stretchable, breakable 2.8 Easy Non-dispersive
0.86% XL-HAd 84 Stretchable, breakable Easy
0.97% XL-HA 71 3.8 Easy 1.6 Easy Non-dispersive
1.08% XL-HA 64 2.9 Easy 1.2 Easy Non-dispersive
1.19% XL-HA 87 1.8 Easy 1.0 Easy Non-dispersive
1.30% XL-HA 71 1.6 Easy 0.7 Easy Non-dispersive
1.41% XL-HA 69 1.2 Easy 0.4 Easy Non-dispersive
1.51% XL-HA 76 0.8 Easy 0.0 Easy Thread-shape
1.62% XL-HA 66 0.3 Easy 0.0 Hard Thread-shape
1.73% XL-HA 59 0.0 Easy 0.0 Hard Thread-shape
0.78% XL-HA (DS: 0.3)c 79 1.2 Breakable 0.0 Easy Non-dispersive
1% HA-cohesive 0 Not tried Impossible 0.0 Very hard Diffusive
Gel-One 0 Not tried Impossible 0.0 Very hard Diffusive
Beriplast P; tenfold diluted 97 19 Stretchable 0.2 Easy Non-dispersive

a[TA Removal, %] = {[Initial TA, 2 mg] – [TA recovered, mg]}/[2 mg] × 100. Removal ability was measured in each sample three times and the average value was recorded

bInjectability was qualitatively assessed using a 1 ml syringe with an attached 27-gauge needle

cHA derivatives prepared as batch 6 (DS: 0.3) were used for the preparation of 0.78% XL-HA

dProperties assessed 10 min after injection into BSS