Figure S5. Volcano plots of differentially expressed genes between two neutrophil subtypes in blood and tumor from NSCLC patients.

The adjusted P-value threshold was set to P < 0.01 with a cutoff for the log₂ fold change (LFC) of 2. (A) CD45^high versus CD45^low low-density neutrophils (LDN) from blood. (B) Blood CD45^low LDN versus tumor-associated neutrophils. (C) Blood CD45^high LDN versus tumor-associated neutrophils. (D) Blood CD45^high LDN versus blood normal-density neutrophils. (A) For each volcano plot, the number of down- and up-regulated genes is indicated for the first neutrophil subtype named in the title (e.g., (A) shows up- and down-regulated genes in CD45^high LDN compared with CD45^low LDN).