Table 4.
Summary of calculated virus reduction factors for low pH treatment step. (Reduction factors [log10] ± 95% confidence index). Reduction factor of samples vs spiked starting material (Sample 1). Note that two replicates were used for each sample that demonstrated as Run 1 & Run 2.
Sample 2 | Sample 3 | Sample 4 | |
---|---|---|---|
Reovirus | Run. 1: 1.08 | Run 1: 3.30 | Run 1: 1.00 |
Run 2: 1.10 | Run 2:3.75 | Run 2: 0.75 | |
Average: 1.09 | Average: 3.52 | Average: 0.87 | |
VSV | Run 1: 1.43 | Run 1: 4.75 | Run 1: 0.75 |
Run 2: 2.50 | Run 2: 4.00 | Run 2: 0.50 | |
Average: 1.96 | Average: 4.37 | Average: 0.63 | |
HSV1 | Run 1: 1.06 | Run 1: 5.33 | Run 1: 0.25 |
Run 2: 1.21 | Run 2: 5.66 | Run 2: 0.50 | |
Average: 1.13 | Average: 5.49 | Average: 0.37 | |
EMCV | Run 1: 1.80 | Run 1: 5.33 | Run 1: 0.25 |
Run 2: 2.16 | Run 2: 5.66 | Run 2: 0.50 | |
Average: 1.98 | Average: 5.49 | Average: 0.37 |