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. 2023 Sep 15;129(9):1477–1489. doi: 10.1038/s41416-023-02418-4

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Fig. 4 — a, b Effects of BEX1 on oxygen consumption ratio (OCR) in Huh-6 and HepG2 cells with treatments as indicated. O oligomycin, F FCCP (carbonyl cyanide 4-[trifluoromethoxy] phenylhydrazone), A&R antimycin A and rotenone. c Relative glucose uptake was determined in Huh-6 and HepG2 cells with treatment as indicated. d Relative lactate production was determined in Huh-6 and HepG2 cells with treatment as indicated. e Relative ATP production was determined in Huh-6 and HepG2 cells with treatment as indicated. f MTS assays in Huh-6 and HepG2 cells with treatment as indicated (EV empty vector, BEX1 expression vector encoding BEX1, galactose, glucose in the culture medium was replaced by galactose). g Colony formation assays in Huh-6 and HepG2 cells with treatment as indicated. h Spheroid formation assays were performed in Huh-6 and HepG2 cells with treatments as indicated. LC-MS: ultra-high-performance liquid-chromatography mass spectrometry. Scale bars: 20 μm.*P < 0.05.