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. 2023 Nov 6;6:241. doi: 10.1038/s42004-023-01043-9

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© The Author(s) 2023

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Fig. 3 — a Scallop-derived PL extract (called scPL70) forms vesicular membrane structures (PL-V) obtained upon dispersion of the lamellar liquid crystalline phase by PEGylated agent TPGS-PEG₁₀₀₀. b, c Cubosome (PL-C) and hexosome (PL-H) types of LNPs are obtained by embedding synthetic docosahexaneoyl (DHA) glycerophospholipid PL-DHA-PE in self-assembles mixtures with hydrated monoolein at MO/PL-DHA-PE molar ratio 85/15 mol/mol (see Table S1 for the compositions of scPL70- and PUFA-plasmalogen-based formulations). Aqueous phase: 1 × 10⁻² M phosphate buffer containing butylated hydroxytoluene (BHT). The temperature is 22 °C. The arrows indicate the positions of the Bragg peaks discussed in the text.