Table 1. Main laboratory data, blood gas analysis, ICU scores and noradrenaline dosage of Case 1, over the acute phase.
| Case 1 | ED (T=0) | ICU (Adm) T1 (3 h) | T2 (6 h) | T3 (12 h) | T4 (24 h) | T5 (30 h) | T6 (36 h) | T7 (48 h) | T8 (60 h) | T9 (72 h) | ICU (D) T11 (96 h) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Lactate (mmol/L) | 8.1 | 9.6 | 11.2 | 13.5 | 9.9 | 8.5 | 4.6 | 2.33 | 1.4 | 1.11 | 0.9 |
| BE (mmol/L) | −21.3 | −23.3 | −25.8 | −23.3 | −18.6 | −15.7 | −11 | −1.2 | 0.8 | 2 | 1.8 |
| PCO2 (mmHg) | 22.3 | 16.1 | 11.7 | 14.3 | 19.5 | 19.8 | 25.8 | 33.3 | 41.1 | 41.9 | 42.8 |
| HCO3− (mmol/L) | 6.4 | 5 | 4 | 5.1 | 7.4 | 9.3 | 13.9 | 22.8 | 25.8 | 26.7 | 26.4 |
| pH | 7.07 | 7.06 | 6.99 | 7.08 | 7.2 | 7.29 | 7.34 | 7.45 | 7.41 | 7.42 | 7.41 |
| AG (mEq/L) | 24 | 27 | 27 | 30 | 28 | 26 | 21 | 14 | 8 | 7 | 9 |
| Creatinine (mg/dL) | 11.2 | 5.8 | – | – | 2.6 | – | – | 2.6 | – | – | 1.9 |
| Glycemia (mg/dL) | 146 | 172 | 186 | 188 | 194 | 182 | 178 | 124 | 161 | 140 | 146 |
| BUN (mg/dL) | 56 | 37.8 | – | – | 28.5 | – | – | 28.5 | – | – | 24.7 |
| eGFR (mL/min/1.73 m2) | 3 | 6.6 | – | – | 18 | – | – | 17.3 | – | – | 25.3 |
| Urine output (mL/kg/h) | – | – | – | – | 0.1 | 0.3 | 0.5 | 0.8 | >1.0 | >1.0 | >1.0 |
| Lipase (U/L) | 268 | 1,830 | – | – | – | – | – | – | – | – | 145 |
| Amylase (U/L) | 78 | 400 | – | – | – | – | – | – | – | – | 76 |
| INR (ratio) | 1.3 | 1.34 | – | – | – | – | – | – | – | – | 1.01 |
| PT (sec) | 1.2 | 14.6 | – | – | – | – | – | – | – | – | 11.4 |
| PTT (sec) | 33 | 27 | – | – | – | – | – | – | – | – | 21 |
| PCT (ng/mL) | 0.41 | 0.5 | – | – | 0.5 | – | – | 0.5 | – | – | 0.3 |
| APACHE II score | 22 | 19 | – | – | – | – | – | 15 | – | – | 13 |
| SOFA score | 10 | 11 | – | – | – | – | – | 9 | – | – | 4 |
| Noradrenaline (mcg/kg/min) | – | 0.24 | 0.35 | 0.42 | 0.35 | 0.28 | – | – | 0.03 | – | |
| Albumin (g/dL) | 3.2 | – | – | – | – | – | – | – | – | – | – |
ICU, intensive care unit; ED, emergency department; Adm, admission; D, discharge; BE, base excess; PCO2, partial pressure of carbon dioxide; AG, anion gap; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; INR, international normalized ratio; PT, prothrombin time; PTT, partial thromboplastin time; PCT, procalcitonin; APACHE, Acute Physiologic Assessment and Chronic Health Evaluation Scoring System; SOFA, Sequential Organ Failure Assessment.