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. 2023 Oct 24;14:1238313. doi: 10.3389/fimmu.2023.1238313

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Copyright © 2023 Yanakieva, Vollmer, Evers, Siegmund, Arras, Pekar, Doerner, Valldorf, Kolmar, Zielonka and Krah

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Structure model of anti-NKp46 IgG1. Surface-exposed AB and EF loops of the CH3 domain are marked in green and cyan, respectively. (B) Structure model of anti-NKp46 IgG with a cattle knob engrafted in the CH3. Anti-EGFR knob H05 engrafted into the AB and EF loops of the CH3 domain are marked in green and cyan, respectively. Figure was generated with PyMOL software version 2.3.0.