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Mass spectrometry analysis of Annexin A2 binding partners with and without the presence of collagen-I (A) Optimization and setup of a workflow to determine Annexin A2 binding partners and how this is affected by the presence of collagen-I. (B) Lists of identified proteins from “Uncoated” (n=357) and “Collagen” (n=378) samples were truncated according to the cut-off of ≥ 4 peptide matches, producing “Collagen ONLY” (n=23) and “Collagen ALL” (n=199) lists for subsequent analysis.
