Table 1.
Summary of studies performed in oocyte donation IVF cycles to determine the impact of advanced age on endometrial receptivity.
Study design |
Reference studies that suggest AA
1 has an impact on ER2 |
Reference studies that suggest AA has no impact on ER | |
---|---|---|---|
First author, year | Detailed conclusion if any | First author, year | |
Oocytes donated by healthy oocyte donors which were transferred to recipients of AA | Abdalla et al. (1990) | – | Balmaceda et al. (1994) |
Meldrum (1993) | The impact of age on ER can be reversed | Sauer et al. (1994) | |
Weckstein et al. (1993) | The impact of age on ER can be reversed | Legro et al. (1995) | |
Yaron et al. (1998) | – | Remohi et al. (1997) | |
Moomjy et al. (1999) | Impact of age on IR3 but not on PR4 and miscarriage rate | Paulson et al. (1997) | |
Toner et al. (2002) | Impact of age on ER after 40 years of age | Mirkin et al. (2003) | |
Soares et al. (2005) | Impact of age on ER after 45 years of age | Wang et al. (2012) | |
Yeh et al. (2014) | Impact of age on ER after 45 years of age | – | |
A single pool of oocytes donated by a young woman and distributed among the recipients with young and AA | Cano et al. (1995) | – | Navot et al. (1994) |
Harris et al. (2002) | AA has a negative impact on the live birth rate but not on PR | Noyes et al. (2001) | |
Infertile patients undergoing IVF who had shared their oocytes with other recipients of advanced age: standard IVF with own oocytes versus IVF with donated oocytes | Levran et al. (1991) | – | Navot et al. (1991) |
Check et al. (1993a) | – | Check et al. (1994) | |
Borini et al. (1996) | – | ||
Braga et al. (2020) | – | – |
AA: advanced age.
ER: endometrial receptivity.
IR: implantation rate.
PR: pregnancy rate.