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. 2023 Oct 24;18(1):20220748. doi: 10.1515/biol-2022-0748

Table 3.

Cox’s proportional hazard regression model for breast cancer–specific survival (BCSS) by subtype and menopausal status

Subtype Breast cancer-specific mortality
Overall Pre-menopausal Post-menopausal
Total Deaths HR Total Deaths HR Total Deaths HR
Luminal-A 90 2 42 1 48 1
<24 35 0 1 19 0 1 16 0 1
≥24 55 2 53.033 23 1 105.823 32 1 38.408
P P = 0.512 P = 0.095 P = 0.376
Luminal-B(HER2−) 591 58 282 8 309 20
<24 236 21 1 139 3 1 97 18 1
≥24 355 37 1.579 143 5 5.170 212 32 1.221
P P = 0.049 P = 0.075 P = 0.661
Luminal-B(HER2+) 116 12 74 10 42 2
<24 55 3 1 39 3 1 26 0 1
≥24 61 9 1.653 35 7 0.850 16 2 42.807
P P = 0.491 P = 0.862 P = 0.551
HER2 overexpression 239 36 124 28 115 8
<24 101 9 1 55 5 1 46 4 1
≥24 138 27 2.966 69 23 4.305 69 4 1.196
P P = 0.007 P = 0.004 P = 0.985
Triple negative 189 63 118 58 71 5
<24 79 24 1 48 22 1 31 2 1
≥24 110 39 2.035 70 36 1.775 40 3 2.151
P P = 0.018 P = 0.048 P = 0.372

Abbreviations: BCSS, breast cancer-specific survival; HR, hazard ratio.