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. 2023 Oct 11;5:100189. doi: 10.1016/j.cccb.2023.100189

Table 2.

Rodent models used within the comorbidity research field.

co-morbidity model Refs.
Ageing samp8 (senescence-accelerated mouse) [34]
Environmental stress models [35]

Hypertension SHRSP (spontaneously hypertensive stroke-prone rats) [36]
SHR (spontaneously hypertensive rats) [37]
Dahl salt-sensitive rats [38]
Angiotensin II-induced hypertension [39]
Salt diet-induced hypertension [40]

Diabetes Mellitus/ Hyperglycaemia db/db mice (obese type 2 diabetes mellitus) [41]
ob/ob mice (obese type 2 diabetes mellitus) [41]
Zucker rats (obese type 2 diabetes mellitus) [42]
Goto-Kakizaki Rat (non-obese type 2 diabetes mellitus) [43]
Streptozotocin- induced type 1 diabetes mellitus [44]
High-fat diet induced obesity [45]

Hyperlipidaemia ApoE KO (apolipoprotein E knock-out) mice [46]
Low-density lipoprotein receptor (Ldlr−/−) knockout mice [47]