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. 2023 Oct 24;14:1258469. doi: 10.3389/fmicb.2023.1258469

FIGURE 1.

FIGURE 1

Bactericidal activity of the peptides against A. baumannii. (A) Killing kinetics of the peptides for the MRAB 0227 and AB 22933 strain. Co-incubation A. baumannii (1 × 105 CFU/mL) with the different concentrations of peptides (0.5 × MIC, 2 × MIC and 8 × MIC) for 0–180 min. Aliquots were collected at 0, 15, 30, 60, 90, 120 and 180 min to count the bacteria. The data are presented as the mean ± SEM (n = 3). * in the figure suggested that no bacteria was detected at this concentration and time; (B) scanning electron micrograph of MRAB 0227 cells (B1) and MRAB 0227 (1 × 105 CFU/mL) treated with 1 × MIC (B2) and 2 × MIC (B3) of 2K4L, 1 × MIC (B4) and 2 × MIC (B5) of 2K2L for 1 h (scale bar = 2 μm, n = 3); (C) atomic force microscope of MRAB 0227 cells (1 × 105 CFU/mL) treated without (control) or in the presence of peptide for 1 h. An analysis of contact mode images was presented. (C-1) topography and (C-2) 3D images; (C-3) section profiles corresponding to red lines in (C-1) (scale bar = 400 nm, n = 3).