Table 2.
Gene | Frequency | N by mutation type |
---|---|---|
TP53 | 38.3% (31/81) | 31 SNVs and 4 indels |
APC | 13.6% (11/81) | 5 SNVs and 6 indels |
KRAS | 9.9% (8/81) | 8 SNVs |
ARID1A | 9.4% (3/32) | 1 SNV and 3 indels |
FBXW7 | 4.9% (4/81) | 4 SNVs |
BRAF | 3.7% (3/81) | 4 SNVs |
FGFR2 * | 6.2% (5/81) | 5 amplifications |
ERBB2 * | 4.9% (4/81) | 4 amplifications |
CCNE1 * | 9.4% (3/32) | 3 amplifications |
KRAS * | 9.4% (3/32) | 3 amplifications |
EGFR * | 3.7% (3/81) | 3 amplifications |
MET * | 3.7% (3/81) | 3 amplifications |
*CNVs were detected in these genes.
Abbreviations: SNV, single-nucleotide variant; CNV, copy number variation.