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. 2023 Nov 6;80(12):1284–1294. doi: 10.1001/jamaneurol.2023.3599

Figure 2. Associations of Apolipoprotein E (APOE)*34 Genotypes With Alzheimer Disease Risk Across Race and Ethnicity, Age, and Sex.

Figure 2.

A-C, The age bin of 60 to 70 years indicated a significant APOE*34-by-sex association in non-Hispanic White individuals that was replicated with nominal significance upon meta-analysis of Hispanic individuals and non-Hispanic Black individuals (P = .048). D, Squares indicate odds ratios (ORs), with horizontal lines indicating 95% CIs. The diamond indicates the pooled OR, with outer points of the diamond indicating 95% CIs.

aP = .01 for interaction.

bP = .08 for interaction.

cP = .25 for interaction.