Table 1.

Baseline demographics and disease characteristics.

	UPA (n = 660)	PBO (n = 328)
Female	248 (37.6)	124 (37.8)
Age, y	41.0 (17-76)	42.0 (17-76)
Caucasian	440 (66.7)	224 (68.3)
Disease duration, y	7.9 ± 6.8	8.2 ± 8.0
Inadequate response to biologics	340 (51.5)	167 (50.9)
No abdominal paina	65 (10.0)	35 (10.8)
No bowel urgencya	49 (7.6)	26 (8.0)
FACIT-F score	30.1 ± 11.7	31.5 ± 11.8

Values are n (%), median (range), or mean ± SD.

Abbreviations: FACIT-F, Functional Assessment of Chronic Illness Therapy–Fatigue; PBO, placebo; UPA, upadacitinib.

^aUPA: n = 647; PBO: n = 325.