Figure 2.

Treatment response. (A) Progression-free (PFS) and overall survival (OS) of patients treated with NK-92/5.28.z cells. Dose levels, time points of initiation of consecutive treatments, and subsequent additional relapse surgeries are indicated. Best response was stable disease (SD) for patients CB001, CB003, CB009, CB010, CB011, and progressive disease (PD) for patients CB004, CB005, CB007. (B) Magnetic resonance imaging (MRI) showing spot-like contrast enhancements in the resection margin in patient CB011 detected 12 and 18 weeks after local NK-92/5.28.z injections as a possible correlate of an induced immune reaction. (C) ¹⁸F-FET positron emission tomography indicating pseudoprogression in patient CB011.