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. 2023 Nov 7;2023(11):CD008628. doi: 10.1002/14651858.CD008628.pub3
Outcome Study ID Measurement tool and time point Surgical; n Conservative; n Effect estimatea
Function in the long term Agren 2013 Composite VAS score for pain and function (0 to 100; higher scores indicate better outcome); participant‐measured scores
At 12 months
Mean (SD): 56.9 (± 26.4); 39 Mean (SD): 54.8 (± 23.7); 37 MD 2.10, 95% CI −9.17 to 13.37
Favours surgical treatment
Analysis 2.1
Function in the long term Agren 2013 OMAS score (0 to 100; higher scores indicate better outcome)
At 12 months
Mean (SD): 62.2 (± 24.2); 39 Mean (SD): 60.9 (± 22.8); 37 MD 1.30, 95% CI −9.27 to 11.87
Favours surgical treatment
Analysis 2.1
Function in the long term Griffin 2014 Kerr‐Atkins score (0 to 100; higher scores indicate better outcome)
At 24 months
Mean (SD): 69.8 (± 21.8); 69 Mean (SD): 65.7 (± 23.7); 74 MD 4.10, 95% CI −3.36 to 11.56
Favours surgical treatment
Analysis 2.1
Function in the long term Kamath 2021 MRS (0 to 100; higher scores indicate better outcome)
At 1 year
Mean (SD): 74.783 (± 11.229); 30 Mean (SD): 57.368 (± 7.335); 31 MD 17.41, 95% CI 12.64 to 22.19; 61 fractures (6 bilateral)
Favours surgical treatment
Analysis 2.1
Function in the long term Kamath 2021 VASb (lower scores indicate better outcome; inverted in analysis)
At 1 year
Mean (SD): 3.348 (± 1.369); 30 Mean (SD): 4.944 (± 0.802); 31 MD 1.60, 95% CI 1.03 to 2.16; 61 fractures (6 bilateral)
Favours surgical treatment
Analysis 2.1
Function in the long term Pandey 2018 VAS: combined pain and function measure (0 to 100; higher scores indicate better outcome)
At 6 months
Mean (SD): 56.73 (± 6.61); 22 Mean (SD): 54 (± 5.19); 20 MD 2.73, 95% CI −0.85 to 6.31
Favours surgical treatment
Analysis 2.1
Chronic pain Agren 2013 VAS during weight‐bearing
At 1 year
Mean (SD): 2.3 (± 2.1); 39 Mean (SD): 2.6 (± 1.6); 37 MD −0.30, 95% CI −1.14 to 0.54
Favours surgical treatment
Analysis 2.2
HRQoL Agren 2013 SF‐36 mental health score
At 1 year
Mean (SD): 52.5 (± 23.3); 39 Mean (SD): 50.5 (± 21.9); 37 MD 2.00, 95% CI −8.16 to 12.16
Favours surgical treatment
Analysis 2.3
HRQoL Griffin 2014 EQ‐5D
At 2 years
Mean (SD): 0.72 (± 0.22); 59 Mean (SD): 0.66 (± 0.27); 62 MD 0.06, 95% CI −0.03 to 0.15
Favour surgical treatment
Analysis 2.3
HRQoL Griffin 2014 SF‐36 mental health score
At 2 years
Mean (SD): 53.4 (± 11.4); 54 Mean (SD): 53.6 (± 12.3); 62 MD −0.20, 95% CI −4.51 to 4.11
Favours non‐surgical treatment
Analysis 2.3
Return to work Parmar 1993 Return to same work
At 1 year
Events: 19; 25 Events: 21; 31 RR 1.12, 95% CI 0.81 to 1.56
Favours surgical treatment
Analysis 2.4
Return to work Thordarson 1996 Return to same work
Within 2 years
Events: 12; 15 Events: 4; 11 RR 2.20, 95% CI 0.97 to 5.00
Favours surgical treatment
Analysis 2.4
Return to leisure activity Parmar 1993 Return to previous recreation level
At 1 year
Events: 16; 25 Events: 23; 31 RR 0.86, 95% CI 0.60 to 1.24
Favours non‐surgical treatment
Analysis 2.4
Return to leisure activity Thordarson 1996 No limitations on daily or recreational activities
Within 2 years
Events: 13; 15 Events: 5; 11 RR 1.91, 95% CI 0.97 to 3.75
Favours surgical treatment
Analysis 2.4