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. 2023 Nov 7;2023(11):CD008628. doi: 10.1002/14651858.CD008628.pub3

Hussain 2022.

Study characteristics
Methods RCT, parallel design, 2‐armed trial
Participants Total number of randomised participants: 32
Source population: single centre, Pakistan
Inclusion criteria: 19 to 67 years of age, Sanders Type II and III closed fractures < 3 weeks old, had normal bipedal gait before injury
Exclusion criteria: calcaneal injuries connected with spinal injuries, pathological fractures, peripheral vasculopathy, or any medical contraindication to surgery, no informed consent
Overall baseline characteristics
  • Sex (M/F): 21/11

  • Type of fracture (Sanders II/III): 52%/48%


Baseline characteristics for surgical group
  • Age, mean: average age 40 years


Baseline characteristics for non‐surgical group
  • Age, mean: average age 42 years

Interventions Surgical group
  • Number randomised: 16

  • Losses (with reasons): 0

  • Number analysed: 16

  • Treatment description: surgery within 2 weeks of injury. Spinal, general, or epidural anaesthetic. Extensile lateral approach used. Use of a single lateral plate. Stayed in hospital with limb in short leg non‐weight‐bearing splint. Weight‐bearing not authorised until 10 weeks postoperatively. Early subtalar RoM activities out of splint


Non‐surgical group
  • Number randomised: 16

  • Losses (with reasons): 0

  • Number analysed: 16

  • Treatment description: closed reduction was tried; short leg casts applied for 6 weeks and RoM exercises performed. In the case of swelling, temporary splint applied with a short leg POP back slab, suggested elevation and anti‐inflammatory and analgesic medications

Outcomes Timing of assessments: 1 year
Outcomes reported in review: pain from exercise (n,%), pain from daily activities (n,%), pain from weight‐bearing (n,%); RoM; restriction from work; Böhler's angle, Gissane angle; function (using MRS: excellent/good/satisfactory/poor); adverse events (delayed wound healing, subtalar arthritis, calcaneal malunion, peroneal tendonitis, heel exostosis)
Other outcomes: gait; radiological union time
Notes Study dates: January 2021 to January 2022
Funding sources: none
Declarations of interest: none
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated random number tables
Allocation concealment (selection bias) Unclear risk No details
Blinding of participants and personnel (performance bias)
All outcomes High risk Due to nature of intervention, treating surgeons and participants were not blinded
Blinding of outcome assessment (detection bias)
All outcomes High risk No details of blinding of outcome assessors, and we assume there was no blinding
Incomplete outcome data (attrition bias)
All outcomes Low risk No apparent losses
Selective reporting (reporting bias) Unclear risk No protocol or clinical trials registration reported. It is not feasible to effectively assess selective outcome reporting without these documents
Other bias Low risk We identified no other sources of bias