Table 6.
Univariate and multivariate analyses of potential prognostic factors on OS in the matched cohort
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95%CI) | P-value | HR (95%CI) | P-value | |
| Treatment | ||||
| IMRT | Reference | |||
| ENPG | 0.772 (0.421–1.414) | 0.402 | ||
| Age at recurrence | 1.049 (1.017–1.083) | 0.003 | 1.046 (1.013–1.081) | 0.006 |
| Pathology | ||||
| Non-keratinizing carcinoma | Reference | |||
| Others | 2.296 (1.091–4.834) | 0.029 | 1.955 (0.924–4.137) | 0.080 |
| Sex | ||||
| Female | Reference | |||
| Male | 0.887 (0.393–2.002) | 0.774 | ||
| Recurrent-free interval | 1.001 (0.996–1.006) | 0.711 | ||
| Recurrent T classification | ||||
| rT3 | Reference | |||
| rT4 | 1.525 (0.844–2.757) | 0.162 | ||
| Recurrent N classification | ||||
| rN0 | Reference | |||
| rN1-3 | 0.880 (0.441–1.756) | 0.716 | ||
| Systemic treatment | ||||
| No | Reference | |||
| Yes | 1.071 (0.475–2.411) | 0.869 |
OS overall survival; ENPG endoscopic nasopharyngectomy; IMRT intensity-modulated radiotherapy