Table 2.
The association between TyG index and three cognitive test scores among nondiabetic older adults
| CERAD test score | Animal Fluency Test score | DSST score | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude | Model 1 | Model 2 | Crude | Model 1 | Model 2 | Crude | Model 1 | Model 2 | |||
| TyG index (continuous) | -1.14 (-2.24, -0.03) * | -1.02 (-2.10, 0.06) | -1.24 (-2.52, 0.03) | -0.71 (-1.77, 0.34) | -0.68 (-1.67, 0.32) | -1.03 (-2.16, 0.10) | -0.38 (-3.84, 3.07) | -0.07 (-3.07, 2.93) | -1.54 (-4.20, 1.11) | ||
| TyG index (quartiles) | |||||||||||
| Q1 | Reference | Reference | Reference | ||||||||
| Q2 | -0.73 (-2.34, 0.89) | -0.54 (-1.88, 0.79) | -0.39 (-1.76, 0.97) | -0.68 (-2.52, 1.16) | -0.61 (-2.22, 1.00) | -0.65 (-2.38, 1.09) | -1.01 (-6.49, 4.45) | -0.02 (-0.11, 0.09) | -0.57 (-4.55, 3.41) | ||
| Q3 | -1.84 (-3.56, -0.11) * | -1.29 (-2.83, 0.25) | -1.15 (-2.81, 0.51) | -1.48 (-3.30, 0.35) | -1.22 (-2.89, 0.45) | -1.09 (-2.67, 0.48) | -3.56 (-9.41, 2.28) | 0.03 (-0.09,0.15) | -1.97 (-6.57, 2.63) | ||
| Q4 | -2.18 (-3.81, -0.55) * | -2.04 (-3.53, -0.55) ** | -2.45 (-4.03, -0.96) ** | -1.25 (-3.04, 0.53) | -1.15 (-2.79, 0.49) | -1.54 (-3.27, 0.18) | -0.63 (-5.89, 4.64) | -0.08 (-0.19, 0.03) | -2.14 (-6.43, 2.15) | ||
Abbreviations: The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD); Digit Symbol Substitution Test (DSST)
Data are presented as β (95% confidence intervals). * P < 0.05. ** P < 0.01
Crude model adjusted for None
Model 1 adjusted for age and gender
Model 2 adjusted for age, gender, BMI, race/ethnicity, educational level, family income-poverty ratio, serum total cholesterol (mg/dl), physical activity, drinking status, smoking status, hypertension, heart failure, coronary heart disease, and stroke
The CERAD test included CERAD-WL and CERAD-DR.